Engine 50 and Truck 12 were organized on May 6, 1901 at 1325 W. Cambria Street. Both companies continue to respond from this house. It is the second oldest firehouse in Philadelphia still in operation. This station also has a swimming pool in the basement. The building has been renovated several times over years. These renovations included the removal of the third floor and mansard roof in 1950.

On April 24, 1984 Rescue 22 moved to Engine 50’s house from Engine 45. Battalion 8 moved in on July 6, 1988.

Three units continue to call this location home, but on November 23, 2019, Battalion 8 moved to Engine 59’s station at 22nd & Hunting Park Avenue.